This is Comodo's description of the "Comodo Secure DNS Configuration" feature!
Here's a tip: Sales pitches are often not technically accurate. It's advertising, for goodness' sake.
Websites load faster because your domain name requests are resolved by our worldwide network of fully redundant DNS servers
DNS lookup is often not the major factor in the speed for which a "page" is loaded by a WWW browser. And a "worldwide network" is flim-flammery. All that the "worldwide network" achieves is putting the proxy DNS server relatively close to you. But you can put it even closer still by the simple expedients of doing things the way that most people do, and obtaining proxy DNS service in the ways outlined later. Ironically, the sales pitch is trying to sell you on benefit of the attempt to compensate for the fact that normally such a service is at a distance disadvantage to how one would normally obtain proxy DNS service.
Highly secure infrastructure reduces your exposure to DNS Cache Poisoning attacks
So, too, does running an ordinary DNS server in accordance with best current practice. Running an instance of Microsoft's DNS server for Windows, properly configured, locally, does the same, but with the benefit that it doesn't hand the keys to the kingdom to someone that you have no reason to trust (more on which later).
Parked, not in use, or commonly misspelled domains are automatically detected and forwarded
This is actually a bad thing. Again, the world learned this lesson in 2003. In addition to my Frequently Given Answer, there are several technical reports that one can find that discuss the problems of automatically generating faked DNS data for mis-spelled and non-existent domain names. This is a huge reason for avoiding Comodo, if anything. Danger, Will Robinson!
If you use Comodo Secure DNS Servers:
Unsurprisingly, what's missing from the sales pitch is the fact that by configuring your machines to use a resolving proxy DNS server from someone like this you are basically handing over full control of your view of the DNS namespace to a third party with whom you have no contractual relationship. The places to obtain proxy DNS service are (a) your own proxy DNS servers that you run, or (b) the proxy DNS servers provided by someone with whom you have a contractal relationship for that service. And as you can see, Comodo isn't someone to trust at all, here. For starters, it wants hi-jack mis-spelled and non-existent domain names and force you to places of its choosing for those names. The Verisign Internet Coup of 2003 is a lesson to learn from.